Alzheimer's disease (AD) is a multifactorial neurodegenerative condition of the central nervous system (CNS) that is currently treated by cholinesterase inhibitors and the N-methyl-d-aspartate receptor antagonist, memantine. ...

Anomaly detection has become an indispensable tool for modern society, applied in a wide range of applications, from detecting fraudulent transactions to malignant brain tumors. Over time, many anomaly detection techniques ...

We consider the static, spherically symmetric and asymptotically flat BPS extremal black holes in ungauged N = 2 D = 4 supergravity theories, in which the scalar manifold of the vector multiplets is homogeneous. By a result ...

We consider an arbitrary metric graph, to which we glue another graph with edges of lengths proportional to ε, where ε is a small positive parameter. On such graph, we consider a general self-adjoint second order differential ...

Optimization plays an effective role in various disciplines of science and engineering. Optimization problems should either be optimized using the appropriate method (i.e., minimization or maximization). Optimization ...

Comparison of the populations and their site conditions in the CR and other European countries showed that all Czech native and artificially established sites are exposed to eutrophication and its consequences, which are ...

Let Ω ⊆ ℝ2 be a domain, let X be a rearrangement invariant space and let f ∈ W1 X (Ω, ℝ2) be a homeomorphism between Ω and f(Ω). Then there exists a sequence of diffeomorphisms fk converging to f in the space W1X (Ω, ℝ2).

We demonstrate how to approximate one-dimensional Schrodinger operators with delta-interaction by a Neumann Laplacian on a narrow waveguide-like domain. Namely, we consider a domain consisting of a straight strip and a ...

Soil water deficit seriously affects crop production, and soil arbuscular mycorrhizal fungi (AMF) enhance drought tolerance in crops by unclear mechanisms. Our study aimed to analyze changes in non-targeted metabolomics ...

Understanding the effects of metabolism on the rational design of novel and more effective drugs is still a considerable challenge. To the best of our knowledge, there are no entirely computational strategies that make it ...