INVESTIGATING THE VARIATIONS IN THE BRAIN ACTIVITY BETWEEN HEALTHY SUBJECTS AND MILD COGNITIVE IMPAIRMENT (MCI) PATIENTS

Abstract

Analysis of brain activity for patients with brain disorders is an important research area. Mild cognitive impairment (MCI) is a condition in which patients have more memory or thinking problems compared to healthy people of the same age. In this work, we studied the alterations in brain activity among control subjects and patients with MCI. Three complexity techniques, namely sample entropy, pproximate entropy, and fractal dimension, were employed to study electroencephalogram (EEG) signals recorded from 102 control (healthy) subjects, and seven subjects with MCI in a comfortable position, on a bed, with their eyes closed. The results showed that the EEG signals of patients with MCI show greater complexity than the EEG signals of healthy subjects. This analysis method can be applied to compare brain activity among healthy subjects and patients with other brain diseases.