Univerzita Hradec Králové: Envíos recientes

  • Tepotinib Inhibits Several Drug Efflux Transporters and Biotransformation Enzymes: The Role in Drug-Drug Interactions and Targeting Cytostatic Resistance In Vitro and Ex Vivo 
    Vagiannis, Dimitrios; Budagaga, Youssif; Morell, Anselm; Zhang, Yu; Novotna, Eva; Skarka, Adam; Kammerer, Sarah; Kupper, Jan-Heiner; Hanke, Ivo; Rozkos, Tomas; Hofman, Jakub (MDPI, 2021)
    Tepotinib is a novel tyrosine kinase inhibitor recently approved for the treatment of non-small cell lung cancer (NSCLC). In this study, we evaluated the tepotinib's potential to perpetrate pharmacokinetic drug interactions ...
  • Special Vinberg cones and the entropy of BPS extremal black holes 
    Alekseevskiy, Dmitry; Marrani, Alessio; Spiro, Andrea (SPRINGER, 2021)
    We consider the static, spherically symmetric and asymptotically flat BPS extremal black holes in ungauged N = 2 D = 4 supergravity theories, in which the scalar manifold of the vector multiplets is homogeneous. By a result ...
  • Problematika vícečetných pohřbů v novověku. Případová studie pohřebiště z 18. století v Semonicích u Jaroměře 
    Drnovský, Pavel; Průchová, Erika (Akademie věd ČR. Archeologický ústav, 2021)
    Studie se věnuje problematice vícečetných hrobů v novověkém období na příkladu výzkumu pohřebiště nedaleko Semonic u Jaroměře (Česká republika, východní Čechy). Záchranný výzkum lokality proběhl v letech 2017–2019. Skupina ...
  • (Un)inhabiting Svalbard: Stories of makings from a transient place in the High Arctic 
    Zhang, Jundan Jasmine; Sokolíčková, Zdenka; Meyer, Alexandra; Vindal Ødegaard, Cecilie; Ferguson, Laura; Iversen, Lisbeth (Universidade da Madeira, 2021)
    The Svalbard archipelago, as well as the Arctic in general, have long been portrayed as pristine nature, harsh and hostile environment, an uninhabitable space for human beings. In reality the Arctic is home to four million ...
  • CZECHS AND SLOVAKS IN SVALBARD: ENTANGLED MODES OF MOBILITY, PLACE, AND IDENTITY 
    Sokolíčková, Zdenka; Soukupová, Eliška (Univerzita Karlova, 2021)
    The article is an anthropological study of how Czech and Slovak nationals reflect on their lives, work, and explorations in Svalbard. We ask what kind of Czech and Slovak “presence” in Svalbard can be documented ethnographically, ...
  • Snow Leopard Optimization Algorithm: A New Nature-Based Optimization Algorithm for Solving Optimization Problems 
    Coufal, Petr; Hubálovský, Štěpán; Hubálovská, Marie; Balogh, Zoltán (MDPI-Molecular diversity preservation international, 2021)
    Numerous optimization problems have been defined in different disciplines of science that must be optimized using effective techniques. Optimization algorithms are an effective and widely used method of solving optimization ...
  • SPECIAL KINDERGARTENS: DOES THE RISK OF BURNOUT DEPEND ON THE PROFESSION? 
    Truhlářová, Zuzana; Havigerová, Jana Marie; Pokorná, Tamara (Univerzita J.E. Purkyně, 2021)
    The aim of the study was to determine the prevalence of burnout syndrome and analyse professional contexts u professional workers of special kindergartens. Research tool: online survey in the range of 11 + 21 items, the ...
  • Analyticity of resolvents of elliptic operators on quantum graphs with small edges 
    Borisov, Denis (Elsevier, 2022)
    We consider an arbitrary metric graph, to which we glue another graph with edges of lengths proportional to ε, where ε is a small positive parameter. On such graph, we consider a general self-adjoint second order differential ...
  • Doubly Charged Higgs Bosons and Spontaneous Symmetry Breaking at eV and TeV Scales 
    Gluza, Janusz; Kordiaczyńska, Magdalena; Srivastava, Tripurari (MDPI, 2020)
    In this paper, beyond standard models are considered with additional scalar triplets without modification of the gauge group (Higgs Triplet Model-HTM) and with an extended gauge group SU(2)R circle times SU(2)L circle times ...
  • Adolf Portmann a jeho relevance pro filosofickou antropologii 
    Novák, Aleš (Akademie věd ČR. Filosofický ústav, 2021)
    Mezi představitele filosofické antropologie bývá řazen také švýcarský biolog a zoolog Adolf Portmann. Studie zkoumá legitimitu tohoto zařazení prostřednictvím analýzy filosofické relevance Portmannova myšlení, a to na ...
  • MLA: A New Mutated Leader Algorithm for Solving Optimization Problems 
    Zeidabadi, Fatemeh Ahmadi; Doumari, Sajjad Amiri; Dehghani, Mohammad; Montazeri, Zeinab; Trojovský, Pavel; Dhiman, Gaurav (Tech Science Press, 2022)
    Optimization plays an effective role in various disciplines of science and engineering. Optimization problems should either be optimized using the appropriate method (i.e., minimization or maximization). Optimization ...
  • Достоевский в контексте истории философии Йиржины Попеловой-Отагаловой 
    Kapičiak, Jakub (Tomskij universitet, 2021)
    Одной из ключевых книг по истории философии чешского философа Йиржины Попе-ловой-Отагаловой является «Распад классической философии» (1968). Философ в ней предлагает подход к развитию философии, начиная с середины XIX в., ...
  • SOCIAL MEDIA FITNESS CHALLENGE – RISKS AND BENEFITS 
    Schlegel, Petr; Křehký, Adam; Dostálová, Radka (Univerzita Komenského, 2021)
    Social media is part of the lives of young adults. Their influence extends to health behavior or nutrition. "Fitness challenges" often appear and they should affect the motivation to exercise, body composition changes, ...
  • Domesticated Water: Four Early Neolithic Wells in Moravia (CZ) 
    Vostrovska, Ivana; Tichý, Radomír; Prichystal, Michal; Muigg, Bernhard; Urbanova, Kristyna; Kalabkova, Pavlina (De Gruyter, 2021)
    Water wells are the most unique finds from the Early Neolithic period in Central Europe. These features provide unusual insight into societies and their settlements, as well as into the water management process. This article ...
  • Raman Spectroscopy as a Novel Method for the Characterization of Polydioxanone Medical Stents Biodegradation 
    Loskot, Jan; Jezbera, Daniel; Bezrouk, Ales; Doležal, Rafael; Andrýs, Rudolf; Francova, Vendula; Miškář, Dominik; Myslivcová Fučíková, Alena (MDPI, 2021)
    Polydioxanone (PPDX), as an FDA approved polymer in tissue engineering, is an important component of some promising medical devices, e.g., biodegradable stents. The hydrolytic degradation of polydioxanone stents plays a ...
  • Differences in Potamogeton praelongus morphology and habitats in Europe 
    Kozelková, Zuzana; Prausová, Romana; Tomášová, Zina; Šafářová, Lenka (Polskie towarzystwo botaniczne, 2021)
    Comparison of the populations and their site conditions in the CR and other European countries showed that all Czech native and artificially established sites are exposed to eutrophication and its consequences, which are ...
  • Presymplectic AKSZ formulation of Einstein gravity 
    Grigoriev, Maxim; Kotov, Oleksii (SPRINGER, 2021)
    Any local gauge theory can be represented as an AKSZ sigma model (upon parameterization if necessary). However, for non-topological models in dimension higher than 1 the target space is necessarily infinite-dimensional. ...
  • Diffeomorphic approximation of planar Sobolev homeomorphisms in rearrangement invariant spaces 
    Campbell, Daniel Cameron; Greco, Luigi; Schiattarella, Roberta; Soudský, Filip (EDP SCIENCES S A, 2021)
    Let Ω ⊆ ℝ2 be a domain, let X be a rearrangement invariant space and let f ∈ W1 X (Ω, ℝ2) be a homeomorphism between Ω and f(Ω). Then there exists a sequence of diffeomorphisms fk converging to f in the space W1X (Ω, ℝ2).
  • Role hudby ve výuce cizích jazyků 
    Košek Bartošová, Iva; Pohnětalová, Yveta (Katolická univerzita, 2021)
    Téma příspěvku prezentuje výsledky výzkumného šetření, jehož cílem bylo zjistit úroveň jazykové paměti u žáků 3., 4. a 5. třídy základní školy a zmapovat roli hudby při výuce cizích jazyků. Pomocí nestandardizovaného ...
  • Zelenohorská jednota a císař Fridrich III. - spojenec, protektor i protivník. 
    Šandera, Martin (Akademie věd ČR. Historický ústav, 2021)
    Studie sleduje vývoj vzájemných vztahů opoziční skupiny české katolické šlechty tzv. zelenohorské ligy a císaře Svaté říše římské Fridricha III. Habsburského, jehož podpora byla vedle papeže k legitimizaci odporu šlechty ...

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