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Tepotinib Inhibits Several Drug Efflux Transporters and Biotransformation Enzymes: The Role in Drug-Drug Interactions and Targeting Cytostatic Resistance In Vitro and Ex Vivo

Vagiannis, Dimitrios; Budagaga, Youssif; Morell, Anselm; Zhang, Yu; Novotna, Eva; Skarka, Adam; Kammerer, Sarah; Kupper, Jan-Heiner; Hanke, Ivo; Rozkos, Tomas; Hofman, Jakub (MDPI, 2021)

Tepotinib is a novel tyrosine kinase inhibitor recently approved for the treatment of non-small cell lung cancer (NSCLC). In this study, we evaluated the tepotinib's potential to perpetrate pharmacokinetic drug interactions ...

Terapeutická intervencia prostriedkami výtvarnej výchovy pre žiakov so syndrómom ADHD

Sedláková, Alena (University of Hradec Kralove, 2021)

Test hudebních schopností u dětí Královéhradeckého dětského sboru se zaměřením na intonační dovednosti

Kroupová, Ludmila; Skopal, Jiří (VERBUM – vydavateľstvo Katolíckej univerzity v Ružomberku, 2024)

Příspěvek pojednává o průzkumu, který si kladl za cíl zmapovat aktuální stav úrovně hudebních schopností u dětí Královéhradeckého dětského sboru. Jsou zde prezentovány výsledky testu zaměřeného především na intonační ...

Text Document Clustering Approach by Improved Sine Cosine Algorithm

Radomirovic, Branislav; Jovanovic, Vuk; Nikolic, Bosko; Stojanovic, Sasa; Kandasamy, Venkatachalam; Zivkovic, Miodrag; Njegus, Angelina; Bacanin, Nebojsa; Strumberger, Ivana (KAUNAS UNIV TECHNOLOGY, 2023)

Due to the vast amounts of textual data available in various forms such as online content, social media comments, corporate data, public e-services and media data, text clustering has been experiencing rapid development. ...

Text-based detection of the risk of depression

Havigerová, Jana Marie; Haviger, Jiří; Kučera, Dalibor; Hofmannová, Petra (Frontiers research foundation, 2019)

This study examines the relationship between language use and psychological characteristics of the communicator. The aim of the study was to find models predicting the depressivity of the writer based on the computational ...

The Analysis of De Minimis Aid Granted in Poland in Years 2008-2015

Bartniczak, Bartosz (University of Hradec Kralove, 2018)

The Analysis of Legal Regulations for Establishing and Operating Reuse Centers or Points

Cvik, Eva Daniela; Hinke, Jana; Kukalová, Gabriela (University of Hradec Kralove, 2024)

The Approach of Czech Business Entities to the Promotion and Application of the Corporate Social Responsibility

Vrabcová, Pavla; Urbancová, Hana (University of Hradec Kralove, 2021)

The Aspect of Ethics Determined by Technological Impact

Paska, Marcin (University of Hradec Kralove, 2021)

The Blue Ocean Strategy in the Context of Management and Development of the Number of Jobs

Galovská, Marcela (University of Hradec Kralove, 2018)

The Brand Identity of a Local Company in the Liberec Region

Beran, Vojtěch; Burešová, Jitka (University of Hradec Kralove, 2023)