Listar por tema "antidotes"

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  • Design, synthesis, in silico studies and in vitro evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators 
    Kitagawa, D.A.S.; Rodrigues, R.B.; Silva, T.N.; dos, Santos W.V.; da, Rocha V.C.V.; de, Almeida J.S.F.D.; Bernardo, L.B.; Carvalho-Silva, T.; Ferreira, C.N.; da Silva, A.A.T.; Simas, A.B.C.; Nepovimová, Eugenie; Kuča, Kamil; Costa Franca, Tanos Celmar; Cavalcante, Samir (Taylor & Francis, 2021)
    Organophosphorus poisoning caused by some pesticides and nerve agents is a life-threating condition that must be swiftly addressed to avoid casualties. Despite the availability of medical countermeasures, the clinically ...
  • In Vitro Evaluation of Neutral Aryloximes as Reactivators for Electrophorus eel Acetylcholinesterase Inhibited by Paraoxon 
    Kitagawa, Daniel A. S.; Cavalcante, Samir; de Paula, Reuel L.; Rodrigues, Rafael B.; Bernardo, Leandro B.; da Silva, Munique C. J.; da Silva, Thiago N.; dos Santos, Wellington, V; Granjeiro, Jose M.; de Almeida, Joyce S. F. D.; Barcellos, Marcos C.; Correa, Ana Beatriz de A.; Costa Franca, Tanos Celmar; Kuča, Kamil; Simas, Alessandro B. C. (MDPI, 2019)
    Casualties caused by organophosphorus pesticides are a burden for health systems in developing and poor countries. Such compounds are potent acetylcholinesterase irreversible inhibitors, and share the toxic profile with ...